Improving Laboratory Testing for Anaphylaxis for Immediate Pragmatic Benefits

When a specific allergen gains acess to the circulation, the allergen can react with basophils of the blood and mast cells in the tissues located immediately outside the small blood vessels, if the basophils and masts cells have been sensitized by the attachment of IgE reagins.  This can be followed by a widespread allergic reaction throughout the vascular system and closely associated tissues, referred to as anaphylaxis, which can lead to forensic consequences.

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Can We Improve Laboratory Testing for Anaphylaxis?

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